This technical note analyzes and explores frameworks for improving interventions in organizations. Organizations are complex ecosystems of assumptions, artifacts, and interactions. By understanding how the current system is arranged and recognizing the broader impacts of any intervention, leaders can make more impactful and lasting changes to their organizations. Any framework is only as good as the assumptions that are baked into it. Often the data needed to answer the questions in this framework are not readily known; therefore, leaders must be open to using methodologies such as ethnography, interviewing, focus groups, and conversations to better solicit these data from key stakeholders.